Truth in Science and Medicine: The Hope and Hype of Stem Cell Therapies
DOI:
https://doi.org/10.12797/RM.02.2021.10.02Keywords:
stem cell therapy, science, medicine, communicationAbstract
The article examines the practice of cell therapies, often named as stem cell therapies. For the general public this is recognized as promising treatment for many diseases, offering hope for many people to restore health to themselves or their loved ones. However, despite the enormous potential that this type of treatment holds, it has its limitations. The tension between hope, science, truth and deception can come to the fore especially when someone is fighting for their life. Moral and ethical issues play a key role in such cases, serving as guideposts obscured, however, by information noise.
References
Blau H.M., Daley G.Q. 2019. Stem Cells in the Treatment of Disease, The New England Journal of Medicine, 380(18), 1748–1760. https://doi.org/10.1056/NEJMra1716145. DOI: https://doi.org/10.1056/NEJMra1716145
EMA Warns Against Using Unproven Cell-Based Therapies. 2020, April 28. European Medicines Agency. Retrieved from: https://www.ema.europa.eu/en/documents/public-statement/ema-warns-against-using-unproven-cell-based-therapies_en.pdf.
Główny Inspektorat Farmaceutyczny. 2020, May 5. Ostrzeżenie EMA przed stosowaniem niepotwierdzonych terapii komórkowych. Retrieved from: https://www.gov.pl/web/gif/ostrzezenie-ema-przed-stosowaniem-niepotwierdzonych-terapii-komorkowych.
Daley G.Q. 2017. Polar Extremes in the Clinical Use of Stem Cells, The New England Journal of Medicine, 376(11), 1075–1077. https://doi.org/10.1056/NEJMe1701379. DOI: https://doi.org/10.1056/NEJMe1701379
De Luca M., Aiuti A., Cossu G., Parmar M., Pellegrini G., Robey P.G. 2019. Advances in Stem Cell Research and Therapeutic Development, Nature Cell Biology, 21(7), 801–811. https://doi.org/10.1038/s41556-019-0344-z. DOI: https://doi.org/10.1038/s41556-019-0344-z
Dulak J., Szade K., Szade A., Nowak W., Józkowicz A. 2015. Adult Stem Cells: Hopes and Hypes of Regenerative Medicine, Acta Biochimica Polonica, 62(3), 329–37. https://doi.org/10.18388/abp.2015_1023. DOI: https://doi.org/10.18388/abp.2015_1023
EASAC report: Challenges and potential in regenerative medicine. 2nd J une 2 020, n o. 4 0. Retrieved from: https://easac.eu/publications/details/challenges-and-potential-in-regenerative-medicine/.
Polska Akademia Nauk. 2020, June 2. Akademie nauk ostrzegają przed „cudownymi” terapiami komórkami macierzystymi. Retrieved from: https://informacje.pan.pl/index.php/informacje/materialy-dla-prasy/3026-akademie-nauk-ostrzegaja-przed-cudownymi-terapiami-komorkami-macierzystymi.
https://clinicaltrials.gov/International Society For Stem Cell Research. 2016 May 12. ISSCR Guidelines for Stem Cell Science and Clinical Translation. Retrieved from: www.isscr.org; http://www.isscr.org/docs/default-source/all-isscr-guidelines/guidelines-2016/isscr-guidelines-for-stem-cell-research-and-clinical-translationd67119731dff6ddbb37cff0000940c19.pdf?sfvrsn=4.
Langrzyk A., Nowak W.N., Stępniewski J., Jaźwa A., Florczyk-Soluch U., Józkowicz A., Dulak J.
July 10. Critical View on Mesenchymal Stromal Cells in Regenerative Medicine, Antioxidants & Redox Signaling, 29(2), 169–190. https://doi.org/10.1089/ars.2017.7159. DOI: https://doi.org/10.1089/ars.2017.7159
Marks P. W., Witten C. M., Califf R. M. 2017 March 16. Claryfying Stem-cell Therapy’s Benefits and Risks, The New England Journal of Medicine, 376(11), 1007–1009. https://doi.org/10.1056/NEJMp1613723. DOI: https://doi.org/10.1056/NEJMp1613723
Mummery C., van de Stolpe A., Roelen B., Clevers H. 2014. Stem Cells. Scientific Facts and Fiction (2nd ed.), London: Academic Press.
Sipp D. et al. 2017 July 5. Marketing of Unproven Stem Cell-based Interventions: A Call to Action, Science Translational Medicine, 9(397). https://doi/org/10.1126/scitranslmed.aag0426. DOI: https://doi.org/10.1126/scitranslmed.aag0426
Srivastava D. 2019 September 4. Don’t Believe Everything You Hear About Stem Cells, Scientific American. Retrieved from: https://blogs.scientificamerican.com/observations/dontbelieve-everything-you-hear-about-stem-cells/.
Szade A. et al. 2019 December 1. Cobalt Protoporphyrin IX Increases Endogenous G-CSF and Mobilizes HSC and Granulocytes to the Blood, EMBO Molecular Medicine, 11(12). https://doi.org/10.15252/emmm.201809571. DOI: https://doi.org/10.15252/emmm.201809571
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